Pathology EMQ template.

Name: Tom MARJOT

Candidate number:

Theme: PANDEMIC FLU

 

OPTION LIST

 

A	Neuraminidase	I	PB2
B	Clara tryptase	J	RNA polymerase
C	Haemagglutinin	K	Furin
D	IFN-gamma	L
E	Oseltamivir	M
F	M2	N
G	Alpha 2,3 sialic acid	O
H	Alpha 2,6 sialic acid	P

 

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

1. A neuraminidase inhibitor, preventing new virion release from host cells; tradename ‘Tamiflu’

 

2. The target for the antiviral ‘amantadine’

 

 

3. A ubiquitous enzyme cleaving haemagglutanin which allows systemic dissemination of H5 and H7 influenza strains.

 

 

4. The major target for avian influenza allowing lower airways colonisation

 

 

5. A recombinant influenza vaccine, ACAM-FLU-A, holds the potential to protect against avian flu and new pandemics by using a component of what well conserved influenza protein?

 

ANSWERS

1. E

2.F

3. K

4. G

5. F